XEOMIN® (incobotulinumtoxinA) is an FDA-approved neurotoxin that thru a State-of-the Art Manufacturing Process block the release of chemicals that cause these muscle contractions, so frown lines are softened. Frown lines form when facial expressions are made as the muscle under the skin contracts. Over time, as your skin ages, these repeated expressions cause lasting frown lines and wrinkles. XEOMIN® is a highly purified treatment that temporarily improves the appearance of moderate to severe frown lines and wrinkles.